A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures 1 to 4 determined by analyses 1D and 2D NMR mass spectroscopic data. identified as (5 E,10 Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), E,9 E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), (-)-loliolide (4) comparing their published antioxidant activities evaluated based on using 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds inactive at concentration 200 μM.